Staff

Kelly A. Keating, Ph.D.

EDUCATION

  • Ph.D. Chemistry, University of California-Davis
  • B.S. Chemistry, University of Wisconsin-Madison

RESEARCH INTERESTS

  • Scientific editing and writing, chemistry, small drug molecules, drug discovery, analytical instrumentation, laboratory management.
Selected Publications
  1. PJ Davis, HY Tang, A Hercbergs, HY Lin, KA Keating, SA Mousa, Bioactivity of thyroid hormone analogs at cancer cells, Front Endocrinol (Lausanne), 2018, 9:739.
  2. H-Y Lin, Y-T Chin, Y-J Shih, Y-R Chen, M Leinung, KA Keating, SA Mousa, PJ Davis, In tumor cells, thyroid hormone analogues non-immunologically regulate PD-L1 and PD-1 accumulation that is anti-apoptotic, Oncotarget, 2018, 9:34033-34037.
  3. SA Mousa, GV Glinsky, H-Y Lin, O Ashur-Fabian, A Hercbergs, KA Keating, PJ Davis, Contributions of thyroid hormone to cancer metastasis, Biomedicines, 2018, 6(3):89.
  4. T Sudha, DJ Bharali, M Yalcin, NH Darwish, M Debreli Coskun, KA Keating, HY Lin, PJ Davis, SA Mousa, Targeted delivery of paclitaxel and doxorubicin to cancer xenografts via the nanoparticle of nano-diamino-tetrac, Int J Nanomedicine, 2017, 12:1305-1315.
  5. T Sudha, DJ Bharali, M Yalcin, NH Darwish, MD Coskun, KA Keating, HY Lin, PJ Davis, SA Mousa, Targeted delivery of cisplatin to tumor xenografts via the nanoparticle component of nano-diamino-tetrac, Nanomedicine (Lond), 2017, 12:195-205.
  6. KA Keating, Tracking health policy reform (2012 AMWA Annual Conference Coverage), in:  AMWA Journal, 2012, pp. e1-e2.
  7. KA Keating, Falsifications and retractions (2012 AMWA Annual Conference Coverage), in:  AMWA Journal, 2012.
  8. KA Keating, Your paper is rejected, now what? (2011 AMWA Annual Conference Coverage), in:  AMWA Journal, 2011, pp. e9-e10.
  9. L Hu, HM Martin, O Arce-Bulted, MN Sugihara, KA Keating, TI Strathmann, Oxidation of carbamazepine by Mn(VII) and Fe(VI): Reaction kinetics and mechanism, Environ Sci Technol, 2009, 43:509-515.
  10. KA Keating, O McConnell, Y Zhang, L Shen, W Demaio, L Mallis, S Elmarakby, A Chandrasekaran, NMR characterization of an S-linked glucuronide metabolite of the potent, novel, nonsteroidal progesterone agonist tanaproget, Drug Metab Dispos, 2006, 34:1283-1287.
  11. LG Marzilli, JS Saad, Z Kuklenyik, KA Keating, Y Xu, Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA, J Am Chem Soc, 2001, 123:2764-2770.
  12. KA Keating, JD Myers, JG Pelton, RA Bair, DE Wemmer, PD Ellis, Development and use of a virtual NMR facility, J Magn Reson, 2000, 143:172-183.
  13. A Schur, KA Keating, DA Payne, T Valdez, KR Yates, JD Myers, Collaborative suites for experiment-oriented scientific research, Interactions, 1998, 5:40-47.
  14. KA Keating, GN La Mar, FY Shiau, KM Smith, 1H NMR study of the molecular and electronic structure of paramagnetic iron chlorin complexes of myoglobin: Dynamic heterogeneity of the heme pocket, J Am Chem Soc, 1992, 114:6513-6520.
  15. L Banci, LB Dugad, GN La Mar, KA Keating, C Luchinat, R Pierattelli, 1H Nuclear magnetic resonance investigation of cobalt(II) substituted carbonic anhydrase, Biophys J, 1992, 63:530-543.
  16. KA Keating, JS De Ropp, GN La Mar, AL Balch, FY Shiau, KM Smith, Assignment by 2D NMR bond correlation spectroscopy of hyperfine-shifted and strongly relaxed protons in iron porphyrin and chlorin complexes, Inorg Chem, 1991, 30:3258-3263.
  17. BK Teo, K Keating, YH Kao, Observation of plasmon frequency in the optical spectrum of Au18Ag20 cluster: The beginning of the collective phenomenon characteristics of the bulk?,
    J Am Chem Soc, 1987, 109:3494-3495.
  18. GK Wertheim, J Kwo, BK Teo, KA Keating, XPS study of bonding in ligated Au clusters,
    Solid State Commun, 1985, 55:357-361.
  19. BK Teo, K Keating, Novel triicosahedral structure of the largest metal alloy cluster: Hexachlorododecakis(triphenylphosphine)-gold-silver cluster {(Ph3P)12Au13Ag12Cl6}m+, J Am Chem Soc, 1984, 106:2224-2226.
Patents
  1. Shen L, Keating K, McConnell O, DeMaio W, Chandrasekaran A, inventors; Wyeth, assignee. Tanaproget derivatives, metabolites, and uses thereof. US patent 7,569,679. August 4, 2009.
Awards
  • Wyeth Chemical and Screening Sciences Above and Beyond Award, 2004
  • AT&T Bell Laboratories Exceptional Contribution Award, 1985
Professional Organizations
  • American Chemical Society
  • American Medical Writers Association
Previous Positions or Appointments
  • Senior Research Specialist (Interim Director), Roy J. Carver Metabolomics Center, University of Illinois Urbana-Champaign
  • Senior Research Scientist II, Wyeth, Collegeville, PA, Manager of NMR labs and spectroscopy services (IR, CHN) for 65 chemists
  • Visiting NMR Scientist and Senior Research Scientist, Pacific Northwest National Laboratory (PNNL), Richland, WA
  • Postdoctoral Research Associate and Graduate Lecturer, Emory University, Atlanta, GA
  • Senior Support Scientist, Biosym Technologies, Inc. (now Accelyrs), San Diego, CA
  • Senior Technical Associate, AT&T Bell Laboratories, Murray Hill, NJ

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